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Updated: Jun 10, 2026

Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine
Published on: February 16, 2018
Synthesis of 5-amino-oxazole-4-carboxylates from alpha-chloroglycinates
Jianmin Zhang1, Pierre-Yves Coqueron, Jean-Pierre Vors
1Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, BC V6T 1Z1, Canada.
Abstract:
Aluminum-based Lewis acids are effective promoters of the condensation of alpha-chloroglycinates with isonitriles or with cyanide ion, leading to the formation of 5-amino-oxazoles.
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