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Updated: Jun 10, 2026

Exploring the Application of Surface-enhanced Raman Scattering-based Biosensing of Individual sEVs in Disease Diagnosis and Therapeutics
Published on: March 13, 2026
Graphene-based SELDI probe with ultrahigh extraction and sensitivity for DNA oligomer
Lena Ai Ling Tang1, Junzhong Wang, Kian Ping Loh
1Department of Chemistry, National University of Singapore, 3 Science Drive 3, 117543, Singapore.
Abstract:
We demonstrate that graphene can be used as an ultrahigh efficiency preconcentration and detection platform for ssDNA. DNA-adsorbed graphene can be used directly for Surface Enhanced Laser Desorption Ionization-Time of Flight-Mass Spectrometry (SELDI-TOF-MS). The rapid enrichment of biomolecules and direct, label-free detection are potentially useful for analysis in proteomics and genomics.
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