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Related Concept Videos

Knee Joint01:23

Knee Joint

The knee joint is the most complicated joint in the body. It consists of three articulations– two tibiofemoral and one patellofemoral. As is characteristic of synovial joints, the knee joint has a thin articular capsule that partially surrounds this joint cavity. Additionally, several ligaments, muscles, and cartilaginous structures support the movement of the knee.
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris group...
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Ankle Joint01:10

Ankle Joint

The ankle is formed by the talocrural joint (crural = leg). It consists of the articulations between the talus bone of the foot and the distal ends of the tibia and fibula of the leg. The superior aspect of the talus bone is square-shaped and has three areas of articulation. The top of the talus articulates with the inferior tibia. This is the portion of the ankle joint that carries the body weight between the leg and foot. The sides of the talus are firmly held in position by the articulations...
Changes in the Appendicular Skeleton with Age01:09

Changes in the Appendicular Skeleton with Age

The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...

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Related Experiment Video

Updated: Jun 10, 2026

The Transition to an Anterior-Based Muscle Sparing Approach Improves Early Postoperative Function but is Associated with a Learning Curve
09:51

The Transition to an Anterior-Based Muscle Sparing Approach Improves Early Postoperative Function but is Associated with a Learning Curve

Published on: September 7, 2022

Total joint replacement in the elderly patient.

Carl T Talmo1, Claire E Robbins, James V Bono

  • 1Department of Orthopaedic Surgery, New England Baptist Hospital, Tufts University, Boston, MA 02120, USA. ctalmo@nebh.org

Clinics in Geriatric Medicine
|August 12, 2010
PubMed
Summary

Total joint replacement (TJR) effectively treats hip and knee osteoarthritis in the elderly. Careful perioperative management ensures high safety and success rates for older patients undergoing TJR.

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Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint
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Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint

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Related Experiment Videos

Last Updated: Jun 10, 2026

The Transition to an Anterior-Based Muscle Sparing Approach Improves Early Postoperative Function but is Associated with a Learning Curve
09:51

The Transition to an Anterior-Based Muscle Sparing Approach Improves Early Postoperative Function but is Associated with a Learning Curve

Published on: September 7, 2022

Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint
06:06

Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint

Published on: July 22, 2021

Area of Science:

  • Geriatric Medicine
  • Orthopedic Surgery
  • Rehabilitative Medicine

Background:

  • Osteoarthritis of the hip and knee is highly prevalent in the aging population.
  • Total joint replacement (TJR) is a common and effective treatment for hip and knee osteoarthritis.
  • The utilization of TJR procedures is rapidly increasing globally.

Purpose of the Study:

  • To highlight the importance of perioperative issue awareness in healthcare providers for TJR patients.
  • To emphasize the safety and efficacy of TJR in the elderly population.
  • To discuss the management of perioperative considerations in elderly patients undergoing TJR.

Main Methods:

  • Review of current literature on TJR in the elderly.
  • Analysis of perioperative outcomes and complication rates.
  • Discussion of preventative measures and monitoring strategies.

Main Results:

  • TJR significantly improves pain, function, and quality of life in elderly patients.
  • Elderly patients may have a slightly higher susceptibility to perioperative complications.
  • High long-term success rates are achievable with careful perioperative care.

Conclusions:

  • Increased awareness of perioperative issues is crucial for healthcare providers managing TJR patients.
  • Proactive monitoring and preventative strategies ensure patient safety and minimize adverse outcomes in the elderly.
  • TJR remains a safe and highly effective procedure for elderly individuals with hip and knee osteoarthritis.