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Updated: Jun 10, 2026

Controlled Cortical Impact Model for Traumatic Brain Injury
Published on: August 5, 2014
Trauma center designation correlates with functional independence after severe but not moderate traumatic brain
Joshua B Brown1, Nicole A Stassen, Julius D Cheng
1Department of Surgery, University of Rochester School of Medicine, Rochester, New York 14642-8410, USA. mark_gestring@urmc.rochester.edu
Background:
The mortality of traumatic brain injury (TBI) continues to decline, emphasizing functional outcomes. Trauma center designation has been linked to survival after TBI, but the impact on functional outcomes is unclear. The objective was to determine whether trauma center designation influenced functional outcomes after moderate and severe TBI.
Methods:
Trauma subjects presenting to an American College of Surgeons (ACS) Level I or II trauma center with a Glasgow Coma Score (GCS)
Results:
Analysis identified 25,170 subjects (72% severe TBI). After adjusting for covariates, ACS Level I designation was associated with FI (odds ratio: 1.16; confidence interval: 1.07-1.24, p < 0.01) and IE (1.10; 1.03-1.17, p < 0.01) after severe TBI. Trauma center designation was not associated with FI or IE after moderate TBI.
Conclusions:
ACS trauma center designation is significantly associated with FI and IE after severe, but not moderate TBI. Prospective study is warranted to verify and explore factors contributing to this discrepancy.

