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Related Concept Videos

Diabetic Retinopathy01:27

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...

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Updated: Jun 10, 2026

Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability
07:23

Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability

Published on: August 6, 2021

Retinal vein occlusions.

Jost Jonas, Michel Paques, Jordi Monés

    Developments in Ophthalmology
    |August 13, 2010
    PubMed
    Summary
    This summary is machine-generated.

    Retinal vein occlusions (RVOs) are vascular disorders diagnosed using fluorescein angiography (FA) and spectral domain optical coherence tomography (SD-OCT). Treatments include laser, intravitreal steroids, anti-VEGF, and surgery, though more trial data is needed.

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    Last Updated: Jun 10, 2026

    Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability
    07:23

    Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability

    Published on: August 6, 2021

    In Vivo Vascular Injury Readouts in Mouse Retina to Promote Reproducibility
    07:35

    In Vivo Vascular Injury Readouts in Mouse Retina to Promote Reproducibility

    Published on: April 21, 2022

    Area of Science:

    • Ophthalmology
    • Retinal vascular diseases
    • Medical imaging

    Background:

    • Retinal vein occlusions (RVOs) are characterized by retinal vein dilation, hemorrhages, macular edema, and ischemia.
    • Fluorescein angiography (FA) is crucial for diagnosing RVO types and assessing macular edema and ischemia.
    • Spectral domain optical coherence tomography (SD-OCT) quantifies retinal changes and edema, aiding prognosis and treatment guidance.

    Purpose of the Study:

    • To review diagnostic and prognostic tools for RVO.
    • To discuss current and emerging treatment modalities for RVO, including laser, intravitreal injections, and surgery.
    • To highlight the need for further randomized trial data to support treatment efficacy.

    Main Methods:

    • Review of diagnostic imaging techniques: Fluorescein Angiography (FA) and Spectral Domain Optical Coherence Tomography (SD-OCT).
    • Analysis of treatment outcomes from case series and prospective randomized trials.
    • Evaluation of laser photocoagulation, intravitreal steroids, anti-VEGF agents, and surgical interventions.

    Main Results:

    • FA and SD-OCT are essential for RVO diagnosis, classification, and monitoring.
    • Laser photocoagulation is a reference treatment for macular edema in branch RVO.
    • Intravitreal steroids and anti-VEGF drugs show promise in reducing edema and improving vision, while surgery offers potential for lasting effects.

    Conclusions:

    • Current diagnostic tools effectively characterize RVO and guide management.
    • Emerging treatments like intravitreal injections and surgery show positive outcomes, but require further validation.
    • Robust data from randomized trials are necessary to establish definitive treatment protocols for RVO.