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Published on: January 14, 2011

Immunotherapy with enhanced self immune cells

Mathias Oelke1, Jonathan Schneck

  • 1Departments of Pathology and Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

Discovery Medicine
|August 14, 2010
PubMed

Extract: Immunotherapy with empowered self immune cells, also called adoptive immunotherapy, has emerged as an exciting therapeutic modality for the treatment of cancer and infectious diseases over the past decade. Adoptive immunotherapy can be defined as the ex vivo (outside the body) generation and expansion of antigen-specific T cells over a short time period and infusion back into the patients. Currently, it has been evaluated for the treatment of infections with viruses such as cytomegalovirus (CMV), Epstein-Barr virus (EBV), and human immunodeficiency virus (HIV), along with a variety of malignancies, including malignant melanoma and multiple myeloma.

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