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Sweet's syndrome with acute leukemia.

P K Sharma1, R A Schwartz, C K Janniger

  • 1Department of Plastic Surgery, UMDNJ-New Jersey Medical School, Newark 07103-2757.

Cutis
|April 1, 1991
PubMed
Summary
This summary is machine-generated.

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Sweet's syndrome, a rare skin condition, can indicate underlying cancer. This case highlights its occurrence with aplastic anemia, leading to acute leukemia, with lesions responding to laser treatment.

Area of Science:

  • Dermatology
  • Hematology
  • Oncology

Background:

  • Sweet's syndrome, or acute neutrophilic dermatosis, is an uncommon skin disorder.
  • It is most frequently associated with hematologic malignancies like acute myelogenous leukemia.
  • Other cancers, particularly hematopoietic, plasma cell, or lymphoid neoplasms, can also be linked.

Observation:

  • A patient presented with symptoms suggestive of Sweet's syndrome.
  • The patient was initially diagnosed with aplastic anemia.
  • The dermatosis ultimately progressed, indicating the development of acute leukemia.

Findings:

  • The study reports an unusual case of Sweet's syndrome.
  • The patient had a history of aplastic anemia that evolved into acute leukemia.

Related Experiment Videos

  • Individual skin lesions demonstrated a positive response to carbon dioxide laser surgery.

    • Implications:

    • This case expands the known associations of Sweet's syndrome beyond typical leukemias.
    • It underscores the importance of considering hematologic progression in patients presenting with acute neutrophilic dermatosis.
    • Carbon dioxide laser surgery may be a viable treatment option for localized lesions in such cases.