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Updated: Jun 10, 2026

A High-Throughput Electrochemiluminescence 7-Plex Assay Simultaneously Screening for Type 1 Diabetes and Multiple Autoimmune Diseases
Published on: May 29, 2020
New onset type 1 diabetes presenting as ketoacidosis simultaneously presenting with autoimmune hyperthyroidism--a
Victoria Mercer1, Verity Burt, Ketan K Dhatariya
1Department of Medicine, Norfolk and Norwich University Hospital NHS Foundation Trust, Colney Lane, Norwich, NR4 7UY Norfolk, UK.
Abstract:
Autoimmune conditions are common with an estimated prevalence in the UK of 2.5%. The presence of one condition should always prompt the clinician to look for others if new symptoms arise. Autoimmune polyglandular syndromes are well described. However, it is unusual for two or more autoimmune conditions to present simultaneously. We describe a case of two autoimmune conditions--type 1 diabetes and Graves' disease--being diagnosed for the first time in the same individual at the same visit to the emergency department. We suggest that thyrotoxicosis be added to the list of potential precipitants for diabetic ketoacidosis.
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