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Internal jugular vein thrombosis after ovulation induction with gonadotropins
1Division of Reproductive Endocrinology, Cedars-Sinai Medical Center, Los Angeles, California 90048.
Fertility and Sterility
|August 1, 1991
Summary
Ovarian hyperstimulation syndrome can lead to dangerous blood clots in major veins. Prompt heparin treatment resolved thrombosis and allowed a successful twin pregnancy.
Area of Science:
- Reproductive Endocrinology
- Vascular Thrombosis
- Obstetrics
Background:
- Ovarian hyperstimulation syndrome (OHSS) is a potential complication of ovulation induction therapies.
- Thromboembolic events are a rare but serious complication of OHSS.
Observation:
- A case of severe OHSS complicated by internal jugular vein and mediastinal thrombosis is described.
- The patient presented with hemoconcentration and immobility, suspected as causative factors.
Findings:
- Successful treatment was achieved using heparin anticoagulation.
- The patient experienced an uneventful twin pregnancy following the stimulation cycle.
Implications:
- This case highlights the importance of vigilant monitoring for thrombosis in OHSS patients.
- Anticoagulation therapy can be effective in managing OHSS-associated venous thromboembolism.
- OHSS management strategies should consider the risk of thromboembolic complications.
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