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[Unresectable hepatic adenomas. Management by selective hepatic artery embolization]
Gastroenterologie Clinique Et Biologique
|January 1, 1991
Summary
Selective hepatic artery embolization for unresectable hepatic adenoma showed delayed tumor shrinkage, enabling surgery in some cases. While not a definitive treatment, it can facilitate safer surgical resection.
Area of Science:
- Hepatobiliary Surgery
- Interventional Radiology
- Oncology
Background:
- Hepatic adenomas are rare benign liver tumors.
- Unresectable hepatic adenomas pose treatment challenges.
- Surgical resection is the primary treatment, but non-operability is common.
Purpose of the Study:
- To evaluate the efficacy of selective hepatic artery embolization (SHAE) in managing unresectable hepatic adenomas.
- To assess SHAE as a bridge to surgical resection.
- To determine the safety and outcomes of SHAE in this patient cohort.
Main Methods:
- Four patients with unresectable hepatic adenoma underwent SHAE.
- Tumor size and operability were assessed post-embolization.
- Postembolization syndrome and complications were monitored.
Main Results:
- Delayed tumor size reduction observed in 3 out of 4 patients, occurring 6 months post-embolization.
- Two patients became eligible for surgical resection following SHAE.
- One patient experienced reversible acute renal failure post-embolization.
- Inadequate tumor devascularization and residual nodules noted in resected specimens.
Conclusions:
- SHAE is not a satisfactory standalone treatment for hepatic adenomas due to incomplete devascularization.
- Preoperative SHAE can be a valuable tool, potentially enabling safer surgical resection of hepatic adenomas.
- Further research into optimized embolization techniques may improve outcomes.