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Published on: May 17, 2024
Cutaneous features predict paraspinal neurofibromas in neurofibromatosis type 1
Rebecca M Brown1, Laura J Klesse, Lu Q Le
1Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
Abstract:
In neurofibromatosis type 1 (NF-1), malignant transformation of internal plexiform neurofibromas carries a poor prognosis, in part because they are not evident clinically. In this issue, Sbidian et al. describe a novel "NF-1Score" equation that employs four easily observable traits to predict the presence of paraspinal neurofibromas. This tool can identify at-risk patients during regular screening to help reduce mortality.
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