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Related Experiment Video

Updated: Jun 10, 2026

Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials
08:41

Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials

Published on: August 13, 2019

Bone materials available for alveolar grafting.

Joseph Deatherage1

  • 1Department of Oral and Maxillofacial Surgery, University of Alabama at Birmingham, Birmingham, AL 35294-0007, USA. jrddmdmd@msn.com

Oral and Maxillofacial Surgery Clinics of North America
|August 18, 2010
PubMed
Summary

Restoring bony defects has evolved from using animal materials to laboratory-grown bone. This innovation addresses significant clinical challenges in bone regeneration.

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Area of Science:

  • Regenerative medicine
  • Biomaterials science
  • Orthopedic surgery

Background:

  • Bone defects pose significant clinical challenges.
  • Historical approaches to bone defect restoration have evolved over time.

Purpose of the Study:

  • To review the historical progression of techniques for restoring bony defects.
  • To highlight the ingenuity in addressing bone regeneration challenges.

Main Methods:

  • Historical review of bone grafting and tissue engineering techniques.
  • Analysis of material sources, from animal-derived to laboratory-grown bone.

Main Results:

  • Early methods utilized animal-derived materials for bone repair.
  • Modern approaches involve laboratory-grown bone and advanced tissue engineering.

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Computed Tomography and Optical Imaging of Osteogenesis-angiogenesis Coupling to Assess Integration of Cranial Bone Autografts and Allografts
13:16

Computed Tomography and Optical Imaging of Osteogenesis-angiogenesis Coupling to Assess Integration of Cranial Bone Autografts and Allografts

Published on: December 22, 2015

Related Experiment Videos

Last Updated: Jun 10, 2026

Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials
08:41

Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials

Published on: August 13, 2019

Computed Tomography and Optical Imaging of Osteogenesis-angiogenesis Coupling to Assess Integration of Cranial Bone Autografts and Allografts
13:16

Computed Tomography and Optical Imaging of Osteogenesis-angiogenesis Coupling to Assess Integration of Cranial Bone Autografts and Allografts

Published on: December 22, 2015

Conclusions:

  • The field has progressed from basic material substitution to sophisticated tissue engineering.
  • Continued innovation is crucial for overcoming challenges in bone defect restoration.