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Tobacco smoking and hand eczema: a population-based study
B Meding1, M Alderling, K Wrangsjö
1Unit of Occupational and Environmental Dermatology, Institute of Environmental Medicine, Karolinska Institutet, SE-171 76 Stockholm, Sweden. birgitta.meding@ki.se
The British Journal of Dermatology
|August 19, 2010
Summary
Heavy tobacco smoking is linked to a higher prevalence of hand eczema, with more cigarettes smoked correlating to increased risk. This study confirms a dose-response relationship, highlighting smoking as a significant factor in hand eczema development.
Area of Science:
- Dermatology
- Environmental Health
- Epidemiology
Background:
- Tobacco smoking is a potential environmental factor contributing to the development of hand eczema.
- Understanding the relationship between smoking habits and hand eczema is crucial for public health initiatives.
Purpose of the Study:
- To investigate the association between tobacco smoking and the prevalence of hand eczema.
- To determine if a dose-response relationship exists between the intensity of smoking and hand eczema occurrence.
Main Methods:
- A national environmental health survey conducted in 2007 involved mailing questionnaires to 43,905 individuals.
- Response data from 25,851 participants (59% response rate) were analyzed for hand eczema prevalence, smoking status, smoking quantity, history of atopy, and water exposure.
- Statistical analysis, including univariate and multivariate approaches, was used to assess associations and control for confounders.
Main Results:
- A total of 25,428 individuals provided usable data on smoking and hand eczema.
- While 10.0% of regular smokers reported hand eczema versus 9.1% of non-smokers (P=0.0951), a significant dose-response relationship was observed.
- Individuals smoking more than 15 cigarettes daily showed a higher prevalence proportion ratio (PPR) for hand eczema (1.40 in multivariate analysis). A continuous variable analysis revealed a PPR of 1.05 (P < 0.001) for smoking habits.
Conclusions:
- A confirmed association exists between heavy tobacco smoking and an increased prevalence of hand eczema.
- The study identified a significant dose-response relationship, indicating that higher tobacco consumption levels elevate the risk of hand eczema.
- Awareness of smoking as a contributing factor and potential confounders like atopy, age, sex, and water exposure is essential in managing hand eczema.
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