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Related Concept Videos

Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Cancer Survival Analysis01:21

Cancer Survival Analysis

Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
Cancer02:18

Cancer

Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
Tumor Progression02:07

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...

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Related Experiment Video

Updated: Jun 10, 2026

Quantitative Mass Spectrometric Profiling of Cancer-cell Proteomes Derived From Liquid and Solid Tumors
08:08

Quantitative Mass Spectrometric Profiling of Cancer-cell Proteomes Derived From Liquid and Solid Tumors

Published on: February 27, 2015

Cancer biomarkers - current perspectives.

Anant Narayan Bhatt1, Rohit Mathur, Abdullah Farooque

  • 1Division of Radiation Biosciences, Institute of Nuclear Medicine & Allied Sciences, Delhi, India.

The Indian Journal of Medical Research
|August 19, 2010
PubMed
Summary

Advances in cancer biomarker knowledge improve patient management through enhanced detection and treatment efficacy. This review covers current and emerging biomarkers for cancer diagnosis, prognosis, and therapy.

Related Experiment Videos

Last Updated: Jun 10, 2026

Quantitative Mass Spectrometric Profiling of Cancer-cell Proteomes Derived From Liquid and Solid Tumors
08:08

Quantitative Mass Spectrometric Profiling of Cancer-cell Proteomes Derived From Liquid and Solid Tumors

Published on: February 27, 2015

Area of Science:

  • Oncology
  • Biochemistry
  • Molecular Biology

Background:

  • Significant advancements in understanding cancer biomarkers offer opportunities to improve patient management.
  • Technological progress facilitates the examination of numerous potential biomarkers and fuels the development of novel ones.

Purpose of the Study:

  • To provide a concise overview of various cancer biomarkers.
  • To discuss biomarkers for diagnosis, prognosis, and therapeutic applications.
  • To include both established and emerging biomarkers in clinical practice.

Main Methods:

  • Literature review of recent advancements in cancer biomarker research.
  • Categorization of biomarkers including nucleic acids, proteins, metabolites, and cellular parameters.
  • Analysis of biomarker relevance for diagnosis, prognosis, and treatment selection.

Main Results:

  • Cancer biomarkers encompass a wide array of biochemical entities and cellular characteristics.
  • Understanding biomarker relevance is crucial for accurate diagnosis and personalized therapeutic choices.
  • The review highlights existing clinical biomarkers and promising future candidates.

Conclusions:

  • Enhanced knowledge of cancer biomarkers significantly improves early detection and treatment effectiveness.
  • Biomarkers play a critical role in guiding therapeutic decisions for cancer patients.
  • Continued research into novel biomarkers is essential for advancing cancer care.