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Updated: Jun 10, 2026

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Visualization of miniSOG Tagged DNA Repair Proteins in Combination with Electron Spectroscopic Imaging (ESI)
Published on: September 24, 2015
DNA photocleavage by an osmium(II) complex in the PDT window
Yujie Sun1, Lauren E Joyce, Nicole M Dickson
1Department of Chemistry, The Ohio State University, Columbus, Ohio 43210, USA.
Abstract:
The extended pi-delocalization of dppn (benzo[i]dipyrido[3,2-a:2,3-c]phenazine) results in a (3)pipi* state as the lowest triplet excited state in [Os(bpy)(2)(dppn)](2+) (bpy = 2,2'-bipyridine), which generates a (1)O(2) quantum yield of 0.42. Together with its (3)MLCT absorption, this new osmium complex shows efficient DNA cleavage under irradiation of lambda(irr) > or = 645 nm.

