Related Experiment Video
Updated: Jun 10, 2026

07:12
Synthesis and Evaluation of a Ruthenium-based Mitochondrial Calcium Uptake Inhibitor
Published on: October 26, 2017
Responsive and mitochondria-specific ruthenium(II) complex for dual in vitro applications: two-photon (near-infrared)
Hanzhong Ke1, Hongda Wang, Wai-Kwok Wong
1Faculty of Material Science & Chemistry Engineering, China University of Geosciences, Wuhan, Hubei 430074, P. R. China.
Abstract:
A mitochondria-permeable ruthenium(II) complex has been designed as a responsive probe which may be used to sensitize the formation of singlet oxygen (Phi(Delta) = 0.93) and cause local damage in cellulo when exposed to UV and near-infrared laser excitation.

