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Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis
Published on: July 19, 2018
[Clinical application of subcutaneous nephrovesical bypass system]
1Department of Urology, Peking University People's Hospital, Beijing 100044, China. lljun@yeah.net
Summary
Subcutaneous nephrovesical bypass effectively manages ureteral obstruction in advanced cancer patients, preserving renal function and enhancing quality of life. This minimally invasive procedure offers a superior alternative to traditional percutaneous nephrostomy.
Area of Science:
- Urology
- Nephrology
- Surgical Oncology
Background:
- Ureteral obstruction in advanced cancer often necessitates renal function support.
- Percutaneous nephrostomy can lead to complications and reduced quality of life.
Purpose of the Study:
- To evaluate the efficacy of subcutaneous nephrovesical bypass in patients with ureteral obstruction.
- To improve the quality of life for palliative patients compared to definitive percutaneous nephrostomy.
Main Methods:
- A total of 36 advanced cancer patients received 45 subcutaneous nephrovesical bypass tubes.
- The procedure involved percutaneous access to kidney and bladder with a subcutaneous tunnel.
- Post-operative assessment included B-ultrasound, KUB, serum creatinine, and glomerular filtration rate (GFR).
Main Results:
- Successful urinary diversion in all 36 patients, with significant reduction in uronephrosis (0-1.8 cm).
- Post-operative serum creatinine improved (72-173 micromol/L) and GFR increased (25-40 mL/min).
- The bypasses functioned well for 67 to 481 days in 45 stents.
Conclusions:
- Subcutaneous nephrovesical bypass is a simple, minimally invasive technique to protect renal function in ureteral obstruction.
- This method reduces complications associated with percutaneous nephrostomy.
- The procedure significantly improves the quality of life for palliative patients.
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