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Updated: Jun 10, 2026

Software-Assisted Quantitative Measurement of Osteoarthritic Subchondral Bone Thickness
Published on: March 18, 2022
Comparison of measurements by multiple methods or instruments
Douglas M Hawkins1, Abha Sharma
1School of Statistics, University of Minnesota, Minneapolis, Minnesota 55455, USA. dhawkins@umn.edu
Abstract:
Much work has been done on comparison of one device with another, but the problem of comparing three or more devices is less well known. Most existing work has concentrated on the possibilities of a constant relative bias between the devices, or of different linear relationships with the underlying true value. These two possibilities are placed within a hierarchy of models extending them to settings with multiplicative interaction terms. These additional terms can capture departures such as outliers, variance changing with the analyte concentration, and different measurement variances between the devices.
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