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Related Concept Videos

Obesity01:24

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in adipocytes...
Regulation of Food Intake01:30

Regulation of Food Intake

Short-term regulation of food intake primarily involves neural signals from the gastrointestinal (GI) tract, blood nutrient levels, and GI tract hormones. Communication between the gut and brain via vagal nerve fibers plays a significant role in evaluating the contents of the gut. Clinical studies have shown that protein ingestion produces a more prolonged response in these nerve fibers compared to an equivalent amount of glucose. Additionally, the activation of stretch receptors caused by GI...

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Updated: Jun 10, 2026

A Common Marmoset Model of Mother-Infant Intervention for Breastfeeding Disorders in the Presence of Paternal Inhibition and Maternal Neglect
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Preventing obesity during infancy: a pilot study.

Ian M Paul1, Jennifer S Savage, Stephanie L Anzman

  • 1Department of Pediatrics, Penn State College of Medicine, Hershey, Pennsylvania, USA. paul@psu.edu

Obesity (Silver Spring, Md.)
|August 21, 2010
PubMed
Summary
This summary is machine-generated.

Early behavioral interventions for infants can prevent childhood obesity. Combined parent-focused "Soothe/Sleep" and "Introduction of Solids" strategies significantly reduced infant weight-for-length percentiles at one year.

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Published on: November 1, 2019

Area of Science:

  • Pediatrics
  • Public Health
  • Behavioral Science

Background:

  • Over 20% of US children aged 2-5 years are overweight, indicating a need for earlier obesity prevention strategies.
  • Infant feeding and sleep behaviors are critical determinants of early growth and long-term weight trajectories.
  • Parental education on infant cues and feeding practices can influence growth patterns.

Purpose of the Study:

  • To evaluate the independent and combined effects of two parent-focused behavioral interventions on infant growth.
  • To promote healthy infant growth trajectories in the first year of life.
  • To assess the potential of multicomponent behavioral interventions for long-term obesity prevention.

Main Methods:

  • A 2x2 factorial design randomized 160 mother-newborn dyads to receive "Soothe/Sleep" and/or "Introduction of Solids" interventions or no intervention.
  • Interventions were delivered during two nurse home visits.
  • Infant weight-for-length percentiles were measured at one year.

Main Results:

  • Infants receiving both "Soothe/Sleep" and "Introduction of Solids" interventions had significantly lower weight-for-length percentiles at one year (P = 0.009).
  • The mean weight-for-length percentile for infants receiving both interventions was 33rd, compared to 50th-56th percentiles in other groups.
  • This suggests a synergistic effect of the combined interventions on infant growth.

Conclusions:

  • Multicomponent behavioral interventions targeting infant feeding and sleep behaviors show promise for early obesity prevention.
  • Parental guidance on infant cues, sleep, and feeding can effectively modulate infant growth.
  • Early intervention during the first year of life is crucial for establishing healthy growth patterns and potentially preventing childhood obesity.