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Related Experiment Video

Updated: Jun 10, 2026

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)
12:22

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)

Published on: August 4, 2018

Reflectometry with a scanning laser ophthalmoscope.

A E Elsner, S A Burns, G W Hughes

    Applied Optics
    |August 21, 2010
    PubMed
    Summary

    New noninvasive techniques reduce scattered light for accurate retinal densitometry, measuring cone photopigment density differences. These methods improve visualization and minimize artifacts for reliable optical measurements.

    Area of Science:

    • Ophthalmology
    • Optical Physics
    • Physiological Optics

    Background:

    • Retinal densitometry measures photopigment density differences.
    • Accurate measurements are crucial for understanding visual function.
    • Existing techniques can be affected by scattered light and artifacts.

    Purpose of the Study:

    • To describe noninvasive techniques for optimizing reflectometry, specifically retinal densitometry.
    • To reduce scattered light and improve retinal visualization during measurements.
    • To minimize artifacts and enable reliable comparison of results across retinal locations.

    Main Methods:

    • Development of noninvasive techniques for reflectometry.
    • Optimization of retinal densitometry measurements.

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    In Vivo Imaging of Cx3cr1gfp/gfp Reporter Mice with Spectral-domain Optical Coherence Tomography and Scanning Laser Ophthalmoscopy
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    Related Experiment Videos

    Last Updated: Jun 10, 2026

    Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)
    12:22

    Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)

    Published on: August 4, 2018

    Scanning Light Scattering Profiler (SLPS) Based Methodology to Quantitatively Evaluate Forward and Backward Light Scattering from Intraocular Lenses
    06:55

    Scanning Light Scattering Profiler (SLPS) Based Methodology to Quantitatively Evaluate Forward and Backward Light Scattering from Intraocular Lenses

    Published on: June 6, 2017

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    In Vivo Imaging of Cx3cr1gfp/gfp Reporter Mice with Spectral-domain Optical Coherence Tomography and Scanning Laser Ophthalmoscopy

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  • Utilizing a research version of the scanning laser ophthalmoscope for reflectometry and psychophysics.

    • Main Results:

    • Significantly reduced unwanted scattered light during measurements.
    • Enhanced visualization of the retina during the measurement process.
    • Minimized visible artifacts, allowing for comparable results across retinal locations.

    Conclusions:

    • The described noninvasive techniques optimize retinal densitometry.
    • Cone photopigment density difference measurements are dependent on optical configuration.
    • Measurements show greatest cone photopigment density difference near the fovea, decreasing with eccentricity.