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Acquiring Hyperpolarized 129Xe Magnetic Resonance Images of Lung Ventilation
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A new approach in virtopsy: Postmortem ventilation in multislice computed tomography.

Tanja Germerott1, Ulrich S Preiss, Lars C Ebert

  • 1Institute of Forensic Medicine, Center of Forensic Imaging and Virtopsy, University of Berne, Berne, Switzerland. tanja.germerott@irm.unibe.ch

Legal Medicine (Tokyo, Japan)
|August 24, 2010
PubMed
Summary
This summary is machine-generated.

Postmortem mechanical ventilation of lungs improves postmortem computed tomography (CT) imaging. This technique enhances the detection of lung pathologies and differentiates normal changes from disease.

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Area of Science:

  • Forensic Medicine
  • Radiology
  • Pulmonary Pathology

Background:

  • Postmortem lung evaluation using imaging is challenging.
  • Differentiating normal postmortem changes from pathological pulmonary changes is difficult.

Purpose of the Study:

  • To assess the effectiveness of postmortem mechanical ventilation in improving lung imaging.
  • To enhance the detection of pulmonary pathologies and differentiate lung conditions.

Main Methods:

  • Five corpses underwent postmortem mechanical ventilation (40 mbar) via endotracheal tube, larynx mask, or CPAP mask.
  • Postmortem computed tomography (CT) scans were taken before and during ventilation.
  • Lung volumes were measured using segmentation software.

Main Results:

  • Postmortem ventilation decreased lung density and ground glass attenuation but left consolidation unchanged.
  • Mean lung volume increased by 2.10 L.
  • Pathologies like septal thickening and nodules became more detectable.

Conclusions:

  • Intracorporeal postmortem mechanical ventilation enhances the detection of small lung pathologies.
  • This method aids in discriminating between consolidation, ground glass attenuation, and position-dependent density.