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Updated: Jun 10, 2026

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Biofunctionalized Prussian Blue Nanoparticles for Multimodal Molecular Imaging Applications
Published on: April 28, 2015
HSA coated MnO nanoparticles with prominent MRI contrast for tumor imaging
Jing Huang1, Jin Xie, Kai Chen
1Department of Radiology and Bio-X Program, Stanford University, 1201 Welch Road P087, Stanford, CA 94305, USA.
Abstract:
We report in this Communication a facile, two-step surface modification strategy to achieve manganese oxide nanoparticles with prominent MRI T1 contrast. In a U87MG glioblastoma xenograft model, we confirmed that the particles can accumulate efficiently in tumor area to induce effective T1 signal alteration.

