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Microbial adhesion to surface-grafted polyacrylamide brushes after long-term exposure to PBS and reconstituted
Irina Fundeanu1, Henny C van der Mei, Arend J Schouten
1Department of Polymer Chemistry, Zernike Institute of Advanced Materials, University of Groningen, Groningen, The Netherlands.
Abstract:
Polyacrylamide (PAAm) brushes, covalently grafted from silicon wafer surfaces were examined for their ability to inhibit microbial adhesion after long-term exposure to PBS or reconstituted freeze-dried saliva for time intervals from 48 h up to 1 month at 37 degrees C. Microbial adhesion after exposure was studied in a parallel plate flow chamber. Infrared spectra showed that PAAm brushes exhibit good chemical stability upon incubation in both PBS and reconstituted freeze-dried saliva up to 1 month. Reductions in microbial adhesion on PAAm brushes after exposure to PBS or reconstituted freeze-dried saliva varied from 63 to 93% depending on the microbial strain considered, even after 1 month of exposure of the brushes to reconstituted freeze-dried saliva.
