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Updated: Jun 10, 2026

Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet
Published on: November 4, 2015
A neonate with left pulmonary artery thrombosis and left lung hypoplasia: a case report
Nahed O Elhassan1, Christi Sproles, Ritu Sachdeva
1Department of Pediatrics, Neonatology, University of Arkansas for Medical Sciences, College of Medicine, Arkansas Children's Hospital, 1 Children's Way, Slot 512-5, Little Rock, AR 72202-3591, USA. ElhassanNahed@uams.edu.
Introduction:
Spontaneous intrauterine arterial thrombosis and congenital pulmonary hypoplasia are rare conditions and have not been reported to occur together. The literature rather includes two reports of babies with neonatal pulmonary artery occlusion and post-infarction cysts of the lungs.
Case Presentation:
We report a case of a live Caucasian male newborn with left lung hypoplasia that occurred in association with left pulmonary artery thrombosis. Despite a critical neonatal course, including extracorporeal membrane oxygenation, this infant is alive and well at 18 months of age without any neurodevelopmental sequelae or reactive airway disease.
Conclusion:
This association suggests the possibility of an intrauterine vascular event between the fifth and eighth weeks of gestation during early pulmonary artery and lung development.
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