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Updated: Jun 9, 2026

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A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
Published on: July 5, 2022
[Screening for gestational diabetes in Bulgaria--preliminary results]
Summary
Gestational diabetes mellitus (GDM) affects 11.3% of pregnant women in Bulgaria. This pilot study highlights risk factors and supports the need for a national screening program for GDM.
Area of Science:
- Endocrinology
- Obstetrics
- Public Health
Background:
- Gestational diabetes mellitus (GDM) is a significant pregnancy complication.
- Limited data exists on GDM prevalence in Bulgaria.
Purpose of the Study:
- To determine the prevalence of GDM in a Bulgarian population.
- To identify epidemiological differences between women with and without GDM.
Main Methods:
- A pilot study involving 330 pregnant women.
- 2-hour, 75g oral glucose tolerance test (OGTT) using ADA criteria.
- Evaluation of blood glucose, insulin, HbA1c, hsCRP, and lipid parameters.
Main Results:
- GDM prevalence was 11.3%.
- Women with GDM were older, with higher BMI, fasting glucose, insulin, HOMA index, and HbA1c.
- GDM was associated with thyroid disease, early preeclampsia, family history of type 2 diabetes, and PCOS.
Conclusions:
- The prevalence of GDM in this high-risk Bulgarian population is substantial.
- A national screening program for GDM is recommended.
- Selective screening for high-risk individuals is a viable alternative if resources are limited.
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