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Updated: Jun 9, 2026

Covalent Binding of BMP-2 on Surfaces Using a Self-assembled Monolayer Approach
Published on: August 26, 2013
Growth factors: beyond bone morphogenetic proteins
Aaron Nauth1, Peter V Giannoudis, Thomas A Einhorn
1Department of Surgery, Division of Orthopaedics, St. Michael's Hospital, University of Toronto, Toronto, Canada.
Abstract:
The current landscape of growth factors in orthopaedic trauma is dominated by the BMPs, as they are the most extensively studied growth factors in clinical applications pertaining to orthopaedic trauma. Despite this, their application and indications for use in trauma remain controversial. This article highlights a number of selected growth factors, other than BMPs, that are currently being investigated in orthopaedic trauma applications. These growth factors have shown significant promise in preclinical and early clinical investigation.
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