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Updated: Jun 9, 2026

Chemotherapy-induced Vascular Toxicity - Real-time In vivo Imaging of Vessel Impairment
Published on: January 7, 2015
Chemotherapy-related visual system toxicity
1Department of Pharmaceutical Sciences, Temple University School of Pharmacy, Philadelphia, Pennsylvania 19140, USA. robert.raffa@temple.edu
Abstract:
Most, if not all, of the studies that report cognitive impairments in patients who have been treated with cancer chemotherapy also report deficits involving the visual system (e.g., visual-spatial function or visual memory). The visual system seems like a likely susceptible target of cytotoxic drugs. Therefore, some portion of the vision-related cognitive deficits ofchemo fog/chemo brain might result from a direct action of the drugs or from site/site interaction between effects on the visual system and other critical brain regions. This chapter is a succint summary of a more expanded review.
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