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Related Concept Videos

Herniated Intervertebral Disc l: Introduction01:29

Herniated Intervertebral Disc l: Introduction

Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...
Degenerative Disc Disease I: Introduction01:27

Degenerative Disc Disease I: Introduction

Degenerative disc disease is a chronic condition in which intervertebral discs gradually lose structure and function. It is not infectious or autoimmune; rather, it results from age-related biochemical and mechanical changes, influenced by genetic, metabolic, and environmental factors.Structure and Function of DiscsThe spine contains 23 intervertebral discs that absorb load, distribute forces, maintain spacing, and allow flexibility. Each disc consists of a nucleus pulposus, a gel-like core...
Degenerative Disc Disease ll: Pathophysiology01:23

Degenerative Disc Disease ll: Pathophysiology

The symptoms of degenerative disc disease arise from a combination of mechanical compression, vascular compromise, and biochemical inflammation, which together disrupt nerve function and produce pain.Mechanical CompressionDisc degeneration reduces height and elasticity, predisposing to herniation of the nucleus pulposus, a major cause of radicular pain. Herniations may be protrusion (bulging with intact annulus), extrusion (nucleus extends beyond disc but remains connected), or sequestration...

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Related Experiment Video

Updated: Jun 9, 2026

Multilevel Oblique Lumbar Interbody Fusion in Degenerative Lumbar Disc Disease with Instability
11:30

Multilevel Oblique Lumbar Interbody Fusion in Degenerative Lumbar Disc Disease with Instability

Published on: July 25, 2025

Lumbar total disc replacement: a numerical study.

Valeriano Di Mascio1, Chiara M Bellini, Fabio Galbusera

  • 1Department of Structural Engineering, Politecnico di Milano, Milan, Italy.

Journal of Applied Biomaterials & Biomechanics : JABB
|August 27, 2010
PubMed
Summary
This summary is machine-generated.

The Maverick disc prosthesis maintained spinal motion and stress levels at adjacent spinal segments. This finite element analysis shows preserved biomechanics after implantation.

Related Experiment Videos

Last Updated: Jun 9, 2026

Multilevel Oblique Lumbar Interbody Fusion in Degenerative Lumbar Disc Disease with Instability
11:30

Multilevel Oblique Lumbar Interbody Fusion in Degenerative Lumbar Disc Disease with Instability

Published on: July 25, 2025

Area of Science:

  • Spine biomechanics
  • Finite element analysis
  • Prosthetic device evaluation

Background:

  • Adjacent segment disease is a concern after spinal fusion or disc replacement.
  • Understanding the biomechanical impact of disc prostheses is crucial for patient outcomes.

Purpose of the Study:

  • To evaluate the biomechanical effects of the Maverick disc prosthesis.
  • To assess effects at the implanted and adjacent spinal levels using finite element analysis.

Main Methods:

  • A 3D finite element model of the L3-L5 spinal segment was created.
  • Simulated physiological movements (flexion, extension, lateral bending, axial rotation) with applied moments.
  • Compared intact model ROMs with those after Maverick prosthesis insertion using the Panjabi hybrid protocol.

Main Results:

  • Predicted increased range of motion (ROM) at the implanted level.
  • Predicted reduced ROM at the adjacent level.
  • No significant change in von Mises stress at the adjacent level post-implantation.

Conclusions:

  • The Maverick disc prosthesis demonstrated preserved kinematics at the adjacent segment.
  • Numerical results suggest maintained stress levels at the adjacent segment post-insertion.