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Related Experiment Videos

Native valve endocarditis due to Corynebacterium group JK.

B G Moffie1, R A Veenendaal, J Thompson

  • 1Department of Medical Microbiology, University Hospital Leiden.

The Netherlands Journal of Medicine
|December 1, 1990
PubMed
Summary

A rare case of endocarditis caused by Corynebacterium group JK in a dialysis patient affected both aortic and mitral valves. Despite vancomycin treatment, an aortic root abscess formed, confirmed post-mortem.

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Area of Science:

  • Infectious Diseases
  • Cardiology
  • Nephrology

Background:

  • Chronic intermittent hemodialysis patients are susceptible to serious infections.
  • Endocarditis is a severe infection of the heart's inner lining.

Observation:

  • A 32-year-old woman undergoing chronic intermittent hemodialysis developed endocarditis.
  • The infection involved both the native aortic and mitral valves.
  • The causative agent was identified as Corynebacterium group JK.

Findings:

  • Despite a four-week course of vancomycin, treatment was unsuccessful.
  • An aortic root abscess developed, indicating treatment failure and disease progression.
  • The diagnosis was definitively confirmed through autopsy.

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Implications:

  • This case highlights the challenges in treating Corynebacterium group JK endocarditis, especially in immunocompromised patients.
  • It underscores the need for vigilant monitoring and potentially alternative therapeutic strategies in hemodialysis patients with endocarditis.
  • The development of an aortic root abscess signifies a poor prognosis and the aggressive nature of this infection.