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[Tuberculosis sequelae: secondary bacterial infections].

H Shishido1, H Nagai, A Kurashima

  • 1Department of Respiratory Diseases, Tokyo National Chest Hospital, Japan.

Kekkaku : [Tuberculosis]
|December 1, 1990
PubMed
Summary

Bacterial infections are common in patients with pulmonary tuberculosis sequelae. Gram-negative bacilli like Pseudomonas aeruginosa were predominant in hospitalized patients, while Streptococcus pneumoniae and Haemophilus influenzae were more common in non-hospitalized cases.

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Area of Science:

  • Infectious Diseases
  • Pulmonology
  • Microbiology

Context:

  • Bacterial infections are significant complications in patients with pulmonary tuberculosis.
  • Tuberculosis sequelae patients are susceptible to secondary respiratory infections.
  • Understanding causative pathogens is crucial for managing these complex cases.

Purpose:

  • To identify causative microorganisms of bacterial respiratory infections in patients with pulmonary tuberculosis sequelae.
  • To correlate specific pathogens with clinical features and patient outcomes.
  • To recommend appropriate treatment and prophylaxis strategies.

Summary:

  • A study of 63 patients with tuberculosis sequelae identified key respiratory pathogens.
  • Gram-negative bacilli (Pseudomonas aeruginosa, GNF-GNB, GF-GNB) and Staphylococcus aureus were predominant in hospitalized patients.

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  • Streptococcus pneumoniae, Haemophilus influenzae, and Branhamella catarrhalis were more common in non-hospitalized patients.

    • Impact:

    • Highlights differences in causative pathogens between hospitalized and non-hospitalized tuberculosis sequelae patients.
    • Informs targeted treatment and prophylaxis for bacterial respiratory infections in this vulnerable population.
    • Contributes to managing chronic respiratory failure and fatal outcomes in post-tuberculous patients.