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Related Experiment Videos

[Massive transfusion: methods and complications].

L Olmedilla Arnal1, J M Pérez Peña, C Jimeno Fernández

  • 1Servicio de Anestesiología y Reanimación, Hospital Gregorio Marañón, Madrid.

Revista Espanola De Anestesiologia Y Reanimacion
|July 1, 1990
PubMed
Summary
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Massive blood transfusions can cause cellular and biochemical changes in stored blood components. This review examines infusion methods and potential complications, including coagulation issues and metabolic disturbances.

Area of Science:

  • Anesthesiology
  • Transfusion Medicine
  • Biochemistry

Background:

  • Massive blood transfusion is a critical procedure in anesthesiology.
  • Stored blood components undergo significant cellular and biochemical alterations.
  • Understanding these changes is vital for patient safety.

Purpose of the Study:

  • To review cellular and biochemical changes in stored blood components.
  • To analyze infusion methods and their impact on flow rates.
  • To assess the pathophysiology of massive blood transfusion complications.

Main Methods:

  • Literature review of cellular changes during blood storage.
  • Analysis of infusion techniques, including catheter type, infusion systems, and filters.
  • Assessment of transfusion-related complications.

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Main Results:

  • Stored blood components exhibit various cellular and biochemical abnormalities.
  • Infusion parameters significantly influence blood flow rates.
  • Complications include coagulation defects, metabolic derangements, and oxygen transport issues.

Conclusions:

  • Massive blood transfusion management requires careful consideration of blood product storage.
  • Optimizing infusion techniques is crucial to mitigate risks.
  • Awareness of potential complications is essential for anesthesiologists.