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[Xanthogranulomatous pyelonephritis in infancy and childhood. Report of two cases]
A Bertolotti1, F Ronfani, A Steiner
1Unidad de Urología, Hospital de Niños Superiora Sor María Ludovica, La Plata, República Argentina.
Anales Espanoles De Pediatria
|December 1, 1990
Insights
Xanthogranulomatous pyelonephritis is a rare kidney infection. Prompt diagnosis and nephrectomy (kidney removal) proved curative in two pediatric cases.
Area of Science:
- Pediatric Nephrology
- Infectious Diseases
- Surgical Pathology
Background:
- Xanthogranulomatous pyelonephritis (XGP) is a rare, chronic inflammatory condition of the kidney.
- It is characterized by lipid-laden macrophages and often associated with infection and obstruction.
- XGP can present with diverse clinical and radiological findings, posing diagnostic challenges.
Abstract:
We are reporting 2 cases of xanthogranulomatous pyelonephritis in boys of 7 and 2 year-old. The inflammatory lesion had extended to perirenal tissues and appeared as a lumbar abscess in case 1. The kidneys affected were diffusely compromised by the lesion. Both cases showed Proteus mirabilis after microbiologic cultures. Definitive diagnosis was done by pathology examination. Nephrectomy was curative.