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Related Concept Videos

Multiple Comparison Tests01:13

Multiple Comparison Tests

Multiple comparison test, abbreviated as MCT, is a post hoc analysis generally performed after comparing multiple samples with one or more tests. An MCT will help identify a significantly different sample among multiple samples or a factor among multiple factors.
It would be easy to compare two samples using a significance alpha level of 0.05. In other words, there is only one sample pair to be compared. However, it would be difficult to identify a significantly different sample if the number...
Bonferroni Test01:10

Bonferroni Test

The Bonferroni test is a statistical test named after Carlo Emilio Bonferroni, an Italian mathematician best known for Bonferroni inequalities. This statistical test is a type of multiple comparison test to determine which means are different than the rest. Bonferroni test can minimize the Type 1 error by reducing the significance level alpha, which otherwise increases with sample pairs.
The means of different samples are first paired in all possible combinations.
The null hypothesis of the...
Friedman Two-way Analysis of Variance by Ranks01:21

Friedman Two-way Analysis of Variance by Ranks

Friedman's Two-Way Analysis of Variance by Ranks is a nonparametric test designed to identify differences across multiple test attempts when traditional assumptions of normality and equal variances do not apply. Unlike conventional ANOVA, which requires normally distributed data with equal variances, Friedman's test is ideal for ordinal or non-normally distributed data, making it particularly useful for analyzing dependent samples, such as matched subjects over time or repeated measures from...
Test for Homogeneity01:23

Test for Homogeneity

The goodness–of–fit test can be used to decide whether a population fits a given distribution, but it will not suffice to decide whether two populations follow the same unknown distribution. A different test, called the test for homogeneity, can be used to conclude whether two populations have the same distribution. To calculate the test statistic for a test for homogeneity, follow the same procedure as with the test of independence. The hypotheses for the test for homogeneity can be stated as...
One-Way ANOVA01:18

One-Way ANOVA

One-way ANOVA analyzes more than three samples categorized by one factor. For example, it can compare the average mileage of sports bikes. Here, the data is categorized by one factor - the company. However, one-way ANOVA cannot be used to simultaneously compare the sample mean of three or more samples categorized by two factors. An example of two factors would be sports bikes from different companies driven in different terrains, such as a desert or snowy landscape. Here, two-way ANOVA is used...
McNemar's Test01:23

McNemar's Test

McNemar's Test is a nonparametric statistical test used to determine if there is a significant difference in proportions between two related groups when the outcome is binary (e.g., yes/no, success/failure). It is beneficial when we have paired data, such as pre-test/post-test designs, where the same subjects are measured under two different conditions. The test is named after the statistician Quinn McNemar, who introduced it in 1947. It is commonly used in situations where subjects are...

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Related Experiment Video

Updated: Jun 9, 2026

An R-Based Landscape Validation of a Competing Risk Model
05:37

An R-Based Landscape Validation of a Competing Risk Model

Published on: September 16, 2022

Multivariate one-sided multiple comparison procedure with a control based on the approximate likelihood ratio test.

Tsunehisa Imada1, Yoshiro Yamamoto

  • 1Department of Business Management, Tokai University, Kumamoto, Japan. timada@ktmail.tokai-u.jp

Biometrical Journal. Biometrische Zeitschrift
|August 28, 2010
PubMed
Summary

This study introduces a new statistical method for multiple comparisons in multivariate studies. It provides a way to determine critical values and calculate the power of tests in pairwise comparisons, enhancing data analysis accuracy.

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Area of Science:

  • Statistics
  • Biostatistics
  • Clinical Trials

Background:

  • Multiple comparison procedures are essential in statistical analysis to control Type I error rates.
  • Multivariate data analysis requires specialized methods for accurate inference.
  • One-sided tests are frequently used in clinical trials to assess treatment efficacy.

Purpose of the Study:

  • To develop a multiple comparison procedure with a control for multivariate one-sided tests.
  • To derive a formula for critical values in pairwise comparisons.
  • To formulate the power of the proposed multiple comparison procedure.

Main Methods:

  • Utilizing approximate likelihood ratio test statistics (Tang et al., 1989).
  • Deriving a formula for critical values at a specified significance level.
  • Formulating the statistical power of the multiple comparison procedure.

Main Results:

  • A novel formula for determining critical values in multivariate pairwise comparisons.
  • A method for calculating the power of the proposed multiple comparison procedure.
  • Numerical examples illustrating critical values and test power.

Conclusions:

  • The developed procedure offers a robust method for multiple comparisons in multivariate settings.
  • The derived formulas enhance the precision of statistical inference in clinical trials.
  • This work provides valuable tools for researchers analyzing complex datasets.