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Rapid Detection of Fecal Antigen of Helicobacter pylori Infection Based on Double Antibody Sandwich Detection Technology
Published on: May 23, 2025
[Helicobacter pylori infection in 755 patients with digestive complaints: Pasteur Institute, Morocco, 1998-2007]
H A H Joutei1, A Hilali, T Fechtali
1Laboratoire d'Environnement, Faculté des Sciences et Techniques, Université Hassan II, Mohammedia, Maroc. mhhanaa@hotmail.com
Abstract:
We determined the prevalence of Helicobacter pylori infection in 755 patients with digestive complaints identified from laboratory records at the Pasteur Institute, Morocco from 1998 to 2007. Epidemiological factors and gastrointestinal conditions associated with this infection were also studied. All patients underwent endoscopy and diagnosis was by histology examination. The prevalence of H. pylori infection was 69%. The difference in prevalence between the age group 40-50 years and other age groups was statistically significant; gender had no significant association. H. pylori infection was found in 92% of chronic gastritis cases. The prevalence of H. pylori was significantly higher in the antrum (73%) than in the corpus (21%) and the pylorus (6%).
Insights
Helicobacter pylori infection is common in Moroccan patients with digestive issues, affecting 69% of those studied. The infection was most prevalent in chronic gastritis cases and individuals aged 40-50.
Area of Science:
- Gastroenterology
- Infectious Diseases
- Epidemiology
Background:
- Helicobacter pylori (H. pylori) is a significant pathogen causing various gastrointestinal disorders.
- Understanding the prevalence and associated factors of H. pylori infection is crucial for public health in Morocco.
Purpose of the Study:
- To determine the prevalence of H. pylori infection among patients with digestive complaints in Morocco.
- To investigate epidemiological factors and gastrointestinal conditions associated with H. pylori infection.
Main Methods:
- Retrospective analysis of 755 patients with digestive complaints from 1998-2007.
- Endoscopy with histological examination for H. pylori diagnosis.
- Statistical analysis of epidemiological data and gastrointestinal conditions.
Main Results:
- Overall H. pylori infection prevalence was 69%.
- Prevalence was significantly higher in the 40-50 age group compared to other age groups.
- H. pylori was present in 92% of chronic gastritis cases.
- Higher prevalence observed in the antrum (73%) versus corpus (21%) and pylorus (6%).
Conclusions:
- H. pylori infection is highly prevalent in Moroccan patients presenting with digestive complaints.
- Age (40-50 years) and chronic gastritis are significantly associated with H. pylori infection.
- Gastric antrum is the most commonly infected site.
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