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Updated: Jun 9, 2026

Extraction of Aqueous Metabolites from Cultured Adherent Cells for Metabolomic Analysis by Capillary Electrophoresis-Mass Spectrometry
Published on: June 9, 2019
Cancer metabolism: the Warburg effect today
1Departamento de Ciências da Vida, Faculdade de Ciências e Tecnologia, Universidade de Coimbra, Rua dos Estudos, 3001-401 Coimbra, Portugal. leonardo_m_r_ferreira@yahoo.com
Abstract:
One of the first studies on the energy metabolism of a tumour was carried out, in 1922, in the laboratory of Otto Warburg. He established that cancer cells exhibited a specific metabolic pattern, characterized by a shift from respiration to fermentation, which has been later named the Warburg effect. Considerable work has been done since then, deepening our understanding of the process, with consequences for diagnosis and therapy. This review presents facts and perspectives on the Warburg effect for the 21st century.
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