Related Experiment Video
Updated: Jun 9, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
Acute postoperative endophthalmitis in a patient with Darier's disease
Aimee V Chappelow1, Gregory Kosmorsky, Craig Lewis
1Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA.
Abstract:
A 58-year-old man with Darier's disease developed endophthalmitis 3 days following left-sided cataract extraction with intraocular lens implantation. Vitreous cultures were positive for Pseudomonas aeruginosa, similar to previously cultured hyperkeratotic plaques on the patient. Despite emergent vitrectomy and aggressive treatment with systemic, intravitreal, and topical fortified antibiotics, the patient required evisceration 19 days postoperatively. Bacterial overgrowth within hyperkeratotic plaques may increase the risk of endophthalmitis following intraocular surgery in patients with Darier's disease.
More Related Videos
Related Concept Videos
Glaucoma: Overview
Diabetic Retinopathy
Angle Closure Glaucoma: Treatment
Endocarditis II: Clinical Features of Infective Endocarditis
Photoreceptors and Visual Pathways
Endocarditis I: Introduction
