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Updated: Jun 9, 2026

TBase - an Integrated Electronic Health Record and Research Database for Kidney Transplant Recipients
Published on: April 13, 2021
Gene polymorphisms in renal transplantation
Monica Grafals1, Leila Kamal, Daniel Chung
1Division of Transplantation, Lahey Clinic, Tufts University, Burlington, MA 01805, USA. Monica.Grafals@Lahey.org
Abstract:
A vast majority of gene polymorphism studies in renal transplantation focus on short-term outcomes such as acute rejection. The main purpose of this article is to review the literature available and studies that have examined the association between the gene polymorphisms and long-term renal allograft functions. In this review, we focus on commonly reported genes in the renin angiotensin system, transforming growth factor-beta gene, and metalloproteinases on the incidence and progression of chronic renal allograft dysfunction.
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