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Related Concept Videos

Electron Carriers01:24

Electron Carriers

91.7K
Electron carriers can be thought of as electron shuttles. These compounds can easily accept electrons (i.e., be reduced) or lose them (i.e., be oxidized). They play an essential role in energy production because cellular respiration is contingent on the flow of electrons.
Over the many stages of cellular respiration, glucose breaks down into carbon dioxide and water. Electron carriers pick up electrons lost by glucose in these reactions, temporarily storing and releasing them into the electron...
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The Muscular System01:18

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The muscular system is essential to the body's overall structure and function, playing a crucial role in movement, stability, and internal processes. It consists of three distinct types of muscle tissue: the skeletal, the smooth, and the cardiac muscles.
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Carrier Transport01:21

Carrier Transport

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The generation of electrical current in semiconductors is fundamentally driven by two mechanisms: drift and diffusion. These processes are essential for the functionality and performance of semiconductor-based devices.
Drift Current:
The drift of charge carriers is started by an external electric field (E). Charged particles, such as electrons and holes, experience an acceleration between collisions with lattice atoms. For electrons, this results in a drift velocity (vd) given by:
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Carrier-Mediated Transport01:06

Carrier-Mediated Transport

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Carrier-mediated transport is a pivotal process in drug absorption, particularly for lipid-insoluble drugs, and encompasses facilitated diffusion and active transport. Facilitated diffusion allows drugs to move along their concentration gradient without energy expenditure, while active transport utilizes ATP to drive drug movement against this gradient.
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Carrier Generation and Recombination01:22

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Carrier generation is the process by which electron-hole pairs (EHPs) are created within the semiconductor. In direct-bandgap semiconductors, such as gallium arsenide (GaAs), this occurs efficiently when energy absorption prompts valence electrons to leap into the conduction band, leaving behind holes.
This process is given by the generation rate G and is efficient due to the conservation of momentum between the valence band maximum and conduction band minimum.
Indirect generation involves an...
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The ADP/ATP Carrier Protein01:42

The ADP/ATP Carrier Protein

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ADP/ATP carrier or AAC protein is the most abundant carrier protein in the inner mitochondrial membrane. It transports large quantities of ADP and ATP, equivalent to the average human body weight, every day. Among other transporters, ACC protein is one of the best-studied members of the mitochondrial carrier protein family. The ADP/ATP carrier protein comprises two transmembrane helices connected to a loop and a single alpha-helix on the matrix side. It switches between two conformational...
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Related Experiment Video

Updated: Jan 28, 2026

Battery of Behavioral Tests Assessing General Locomotion, Muscular Strength, and Coordination in Mice
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Carrier testing for spinal muscular atrophy.

Jonathan M Gitlin1, Kenneth Fischbeck, Thomas O Crawford

  • 1National Human Genome Research Institute, 31 Center Drive, 4B09, Bethesda, MD 20892-2152, USA. gitlinjm@mail.nih.gov

Genetics in Medicine : Official Journal of the American College of Medical Genetics
|September 3, 2010
PubMed
Summary

Spinal muscular atrophy carrier screening is feasible for newborns. However, professional guidelines conflict, leaving healthcare providers uncertain about routine reproductive care recommendations.

Area of Science:

  • Genetics
  • Neurology
  • Reproductive Medicine

Background:

  • Spinal muscular atrophy (SMA) is a leading fatal hereditary disease in infants.

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  • Currently, no effective treatments exist for SMA.
  • Disagreement among medical societies regarding SMA carrier screening creates uncertainty for healthcare providers.