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Updated: Jun 9, 2026

Minimally Invasive Thumb-sized Pterional Craniotomy for Surgical Clip Ligation of Unruptured Anterior Circulation Aneurysms
Published on: August 11, 2015
Self-closing aneurysm clip: a historical review
Manuel Dujovny1, Celso Agner, Onyekachi Ibe
1Department of Neurosugery, Department of Engeneering, Wayne State University, Detroit, MI, USA. manueldujovny@hotmail.com
Objective:
To analyse the self-closing aneurysm clip historical evolution.
Materials And Methods:
The authors reviewed the self-closing aneurysm clip's 50-year history. Major neurosurgical books, journals, testimonials, authors' personal experience, and scientific databases were analysed.
Results:
Self-closing aneurysm clip malfunction was found to be related to different clip strengths (too strong or too weak) and clip's corrosion or fracture due to diverse stainless steel biocompatibility issues. It was found that 301, 401, 402, 58, and 17-7 PH alloys were not suitable for human implantation due to high risk of corrosion. In counterpart, 316MOSS, Elgiloy, Phynox, and titanium alloys were more biocompatible and less prone to corrosion. The last group showed no motion on the magnetic field. Titanium clip has shown to be artifact free on computerized tomography followed by high-grade cobalt-chromium clip all the other aneurysms clip present a significant artifact. The Federal Drugs and Administration/American Society of Testing and Materials (FDA/ASTM) was a major contributor on safety development of self-closing aneurysm clip.
Conclusion:
Our 36-year self-closing aneurysm clip experience is reported.
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