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Contrast-enhanced dynamic magnetic resonance nephrography in healthy dogs
J M Fonseca-Matheus1, C C Pérez-García, M M D Ginja
1Department of Animal Pathology, Animal Medicine, University, 24071 León, Spain.
Veterinary Journal (London, England : 1997)
|September 3, 2010
Summary
Magnetic resonance (MR) renography in dogs provides detailed urinary excretion parameters. This non-invasive imaging technique offers an alternative to radionuclide methods for canine kidney assessment.
Area of Science:
- Veterinary Radiology
- Diagnostic Imaging
- Canine Nephrology
Background:
- Magnetic resonance (MR) renography is an advanced imaging technique.
- Assessing canine urinary excretion parameters is crucial for diagnosing kidney conditions.
- Radionuclide nephrography is a common but invasive method for evaluating kidney function.
Purpose of the Study:
- To evaluate the feasibility and utility of serial MR renography for assessing urinary excretion parameters in healthy dogs.
- To establish normative time-intensity curve parameters for canine kidneys using MR imaging.
- To compare MR renography with radionuclide nephrography as a diagnostic tool.
Main Methods:
- Twenty-three healthy adult male dogs underwent serial MR renography.
- A dynamic gradient-echo, fast SPGR, T1-weighted sequence with low-dose gadolinium chelates was utilized.
- Time-intensity curves were generated to analyze parameters like time to vascular peak (TVP), time to vascular drop (TVD), time to glomerular peak (TGP), parenchymal phase length (PPL), and gradient of parenchymal phase (GPP).
Main Results:
- Mean TVP, TVD, TGP, and PPL were 31.6±11.8s, 43.4±11.2s, 154.0±36.2s, and 115.2±37.7s, respectively.
- The gradient of parenchymal phase (GPP) averaged 24.1±8.6% signal intensity per minute.
- The excretory segment was consistently concave, with 87.1% of kidneys showing a 50% signal intensity reduction by the study's end.
Conclusions:
- Serial MR renography provides adequate time-intensity curve parameters for evaluating the canine urinary system.
- This MR nephrography protocol offers excellent anatomical detail and serves as a viable alternative to radionuclide nephrography.
- MR renography is a promising non-invasive imaging modality for canine kidney assessment.
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