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Published on: January 8, 2016
Cytidine-Ag+-purine base complexes as studied by electrospray ionization mass spectrometry
1Poznań University of Technology, Institute of Chemistry, Piotrowo 3, 60-965 Poznań, Poland. Magdalena.Franska@put.poznan.pl
Abstract:
The complexes of cytidine (C) with Ag(+) and adenosine (A), guanosine (G), inosine (In) and caffeine (Caf) were studied by electrospray ionization mass spectrometry (ESI-MS). Both collision-induced dissociation (CID) "in- source" and CID MS/MS experiments were performed. The stability of [C + G + Ag](+) and [C + In + Ag](+) ions in the gas phase was found to be much higher than that of [C + A + Ag](+) and [C + Caf + Ag](+) ions. It is reasonable to conclude that guanosine and inosine form bidentate complex with silver cation, by N7 atom and O=C6 oxygen atom, whereas adenosine and caffeine form monodentate complexes, by N3 atom of adenine and N9 atom of caffeine.
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