Related Experiment Video
Updated: Jun 9, 2026
11:35
Dual-mode Imaging of Cutaneous Tissue Oxygenation and Vascular Function
Published on: December 8, 2010
Susceptibility mapping as a means to visualize veins and quantify oxygen saturation
E M Haacke1, J Tang, J Neelavalli
1Department of Radiology, Wayne State University, Detroit, Michigan 48201, USA. nmrimaging@aol.com
Journal of Magnetic Resonance Imaging : JMRI
|September 4, 2010
Summary
This study introduces a new method for creating 3D brain vein images using susceptibility mapping. This technique offers improved visualization of major cerebral veins, aiding in neuroimaging research.
Area of Science:
- Neuroimaging
- Medical Physics
- Radiology
Background:
- Susceptibility Weighted Imaging (SWI) phase images provide information on local magnetic field behavior.
- Standard SWI is sensitive to vessel orientation and geometry, complicating quantitative analysis.
- Developing orientation-independent methods is crucial for accurate venous characterization.
Purpose of the Study:
- To develop an orientation-independent, 3D reconstruction of brain veins using susceptibility mapping.
- To overcome limitations of traditional SWI in visualizing and quantifying venous structures.
- To create a robust venographic tool for neuroimaging applications.
Main Methods:
- Utilized high-resolution, high-pass filtered phase images from SWI.
- Applied an inverse procedure to generate susceptibility maps, effectively creating venograms.
- Employed k-space regularization and interpolation to minimize reconstruction artifacts.
- Conducted simulations of blood vessels to validate and refine the methodology.
Main Results:
- Successfully visualized major brain veins with orientation independence.
- Removed geometry-dependent phase dipole effects, isolating venous signals.
- Observed varying contrast-to-noise ratios based on vessel size and partial volume effects.
- Quantitative susceptibility values for larger vessels (8-16 mm) approximated expected levels for normal oxygen saturation.
Conclusions:
- Susceptibility mapping enables successful venography of the brain.
- The technique's utility as an imaging or visualization tool is influenced by partial volume effects.
- Larger vessels demonstrated susceptibility values close to those expected for normal blood oxygen saturation levels.
More Related Videos
14:28Non-Invasive Monitoring of Microvascular Oxygenation and Reactive Hyperemia using Hybrid, Near-Infrared Diffuse Optical Spectroscopy for Critical Care
Published on: May 10, 2024
08:26Quantitative Mapping of Specific Ventilation in the Human Lung using Proton Magnetic Resonance Imaging and Oxygen as a Contrast Agent
Published on: June 5, 2019
Related Concept Videos
01:19Special considerations while measuring oxygen saturation
Assessing respiratory rate concurrently with pulse measurement is fundamental to patient care, providing valuable insights into the patient's respiratory function. The normal breathing rate for an adult usually falls within a normal range of 12 to 20 breaths per minute. Abnormal respiratory rates can signal underlying health conditions or the need for immediate intervention.
Ensuring accuracy in vital sign recordings while prioritizing patient comfort and minimizing anxiety is important.
Ensuring accuracy in vital sign recordings while prioritizing patient comfort and minimizing anxiety is important.
01:17Assessment of Diffusion and Perfusion
Understanding and evaluating diffusion and perfusion is critical in assessing a patient's respiratory and circulatory health. These processes play key roles in maintaining the body's internal environment, ensuring that tissues receive adequate oxygen while waste products are efficiently removed.
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this principle...
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this principle...
01:19Guidelines For Measuring Vital Signs
Following these guidelines can help nurses accurately measure vital signs, assess changes in patient conditions, and provide timely treatment when necessary. Adhering closely to the guidelines ensures the accuracy and reliability of the results.
Before taking a patient's vital signs, a nurse would consider and assess the patient's comfort level and ensure appropriate equipment is available.
Before taking a patient's vital signs, a nurse would consider and assess the patient's comfort level and ensure appropriate equipment is available.
01:20Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
01:17Veins of Upper Limbs
The human circulatory system, a marvel of biological engineering, is a complex network of vessels that transport blood throughout the body. Among these, the veins responsible for carrying blood from the upper limbs are divided into two categories: deep and superficial.
The deep venous system is primarily composed of the ulnar and radial veins. The ulnar vein, which drains the fingers through the superficial palmar venous arches, and the radial vein, which serves the palms via the deep palmar...
The deep venous system is primarily composed of the ulnar and radial veins. The ulnar vein, which drains the fingers through the superficial palmar venous arches, and the radial vein, which serves the palms via the deep palmar...
01:15Veins of Lower Limbs
The human body consists of an intricate network of veins responsible for the crucial task of blood drainage from the lower limbs. These veins can be categorized into two main types: deep veins and superficial veins.
Formed by the union of the medial and lateral plantar veins, the posterior tibial vein, rising through the calf muscle, assimilates the fibular vein. The anterior tibial vein, a superior extension of the foot's dorsalis pedis vein, merges with the posterior tibial vein at the knee,...
Formed by the union of the medial and lateral plantar veins, the posterior tibial vein, rising through the calf muscle, assimilates the fibular vein. The anterior tibial vein, a superior extension of the foot's dorsalis pedis vein, merges with the posterior tibial vein at the knee,...