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Extent and burden of allergic diseases in elementary schoolchildren: a national multicenter study
1Hacettepe University, Faculty of Medicine, Department of Pediatric Allergy and Asthma, Ankara, Turkey.
Insights
Approximately one-third of Turkish schoolchildren experience allergic disease symptoms annually. This study highlights regional variations and diagnostic challenges in childhood allergies, emphasizing the need for objective data collection.
Area of Science:
- Pediatric Allergy and Immunology
- Epidemiology
- Public Health
Background:
- Limited standardized data on childhood allergic diseases in Turkey necessitates multicenter studies.
- Objective tools are crucial to enhance the validity and reliability of allergy research in schoolchildren.
- Previous research highlights the need for better diagnostic and treatment strategies for pediatric allergic conditions.
Purpose of the Study:
- To determine the prevalence of allergic diseases among elementary schoolchildren in Turkey.
- To investigate regional variations in allergic disease symptoms and objective signs.
- To assess the impact of allergic diseases on school absenteeism.
Main Methods:
- Utilized International Study of Asthma and Allergies in Children (ISAAC) Phase II tools for data collection.
- Surveyed 6963 children aged 9-11 years across 5 major Turkish cities.
- Employed parental reports and objective diagnostic tools to assess allergic conditions.
Main Results:
- 35% of surveyed children reported at least one allergic disease symptom in the past year.
- Prevalence rates: wheezing (15.8%), rhinoconjunctivitis (23.5%), eczema (8.1%), atopy (18.9%), flexural dermatitis (3.6%), bronchial hyperreactivity (24.2%).
- Significant interregional variations in symptom and objective sign prevalence were observed; 34.2% of children with asthma/allergic rhinitis experienced school absence.
Conclusions:
- About one-third of Turkish elementary schoolchildren exhibit symptoms consistent with allergic diseases.
- Interregional disparities in allergic disease prevalence may be linked to environmental factors.
- Challenges persist in the timely and accurate diagnosis and management of allergic diseases in children.
Background:
Scarcity of standardized, comparable data on allergic diseases in schoolchildren in Turkey requires further multicenter studies based on the use of objective tools in addition to parent-completed questionnaires to improve the validity and reliability of results.
Methods:
Using International Study of Asthma and Allergies in Children (ISAAC) Phase II tools, elementary schoolchildren aged 9 to 11 years were surveyed in 5 city centers in different regions of Turkey.
Results:
We surveyed 6963 children from 70 schools and found that 35% had had at least 1 symptom of allergic diseases in the past year. Based on parental reports, the overall prevalence rates for wheezing, rhinoconjunctivitis, and eczema in the past year were 15.8%, 23.5%, and 8.1%, respectively. The overall frequencies of atopy, flexural dermatitis, and bronchial hyperreactivity were 18.9%, 3.6%, and 24.2%, respectively. There were large variations in the prevalence of both symptoms and objective signs between study centers. Absence from school for at least 1 day was reported for 34.2% of children with a diagnosis of asthma or allergic rhinitis.
Conclusions:
Approximately one third of elementary schoolchildren reported symptoms compatible with allergic diseases in the past year. The interregional differences in both symptoms and objective test results are possibly due to differences in environmental conditions. Unfortunately, serious problems are still encountered in the timely and proper diagnosis and treatment of allergic diseases.
Related Concept Videos
Asthma I: Introduction
Allergic Reactions
Allergic Reactions: Anaphylaxis
Asthma-III: Symptoms and Complications
Classification of Asthma
Asthma-II: Pathophysiology and Classification
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Asthma-I: Introduction

