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3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

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Published on: June 2, 2014

Migraine--clinical neurophysiology.

Anna Ambrosini¹, Delphine Magis, Jean Schoenen

¹Headache Clinic, INM Neuromed, IRCCS, Pozzilli (Isernia), Italy.

Handbook of Clinical Neurology

|September 7, 2010

Summary

Neurophysiological testing reveals central nervous system dysfunction in migraine patients. While valuable for understanding migraine mechanisms, its high variability limits diagnostic use.

Area of Science:

Neuroscience
Neurology
Clinical Neurophysiology

Background:

Migraine is linked to central nervous system (CNS) dysfunction affecting brain, brainstem, and peripheral structures.
Neurophysiological testing offers functional evaluation of nervous system components.

Purpose of the Study:

To critically review and summarize neurophysiological approaches in migraine research.
To highlight techniques most relevant for understanding migraine pathophysiology.

Main Methods:

Review of published literature on neurophysiological methods in migraine.
Inclusion of electroencephalography, evoked and event-related potentials, transcranial magnetic stimulation (TMS), electromyography, and cerebellar testing.

Main Results:

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Neurophysiological testing is a valuable tool for investigating migraine pathophysiology and treatment effects.
High interindividual variability limits the diagnostic value of these tests for migraine.

Conclusions:

Neurophysiological techniques are crucial for elucidating migraine pathophysiological mechanisms.
Further research may refine the application of these methods in migraine management.