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Related Concept Videos

Decreased Body Temperature01:29

Decreased Body Temperature

A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by sustained extreme cold exposure, and severe...
Ischemic Stroke ll: Pathophysiology01:15

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An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...
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Transient Ischemic Attack l: Introduction

A transient ischemic attack (TIA) is a brief episode of neurological dysfunction caused by a temporary, focal reduction in cerebral blood flow. Although symptoms resemble those of an ischemic stroke, the interruption in perfusion is short-lived and does not cause permanent infarction. TIAs are clinically important because they often serve as early warning events for future stroke.Mechanisms of Transient Cerebral IschemiaTransient cerebral ischemia may arise through several mechanisms. One...
Acute Kidney Injury V: Interprofessional Care01:20

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Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
Methods of reducing fever01:22

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The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
Pharmacological Methods of Reducing Fever:
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Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...

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Related Experiment Video

Updated: Jun 9, 2026

Short-Duration Hypothermia Induction in Rats using Models for Studies examining Clinical Relevance and Mechanisms
05:00

Short-Duration Hypothermia Induction in Rats using Models for Studies examining Clinical Relevance and Mechanisms

Published on: March 3, 2021

Therapeutic hypothermia is associated with a decrease in urine output in acute stroke patients.

Kama Z Guluma1, Lin Liu, Thomas M Hemmen

  • 1Department of Emergency Medicine, University of California San Diego Medical Center, 200 West Arbor Drive, San Diego, CA 92103-8676, United States.

Resuscitation
|September 7, 2010
PubMed
Summary
This summary is machine-generated.

Therapeutic hypothermia in awake patients reduced urine output correlated with temperature drop, but did not affect kidney function markers. Careful fluid management is crucial during hypothermia treatment.

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Last Updated: Jun 9, 2026

Short-Duration Hypothermia Induction in Rats using Models for Studies examining Clinical Relevance and Mechanisms
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Published on: March 3, 2021

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management
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A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
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Published on: August 18, 2015

Area of Science:

  • Nephrology
  • Cardiovascular Physiology
  • Therapeutic Hypothermia

Background:

  • Therapeutic hypothermia's renal effects are unclear due to confounding factors in prior studies.
  • Previous research often involved patients with compromised cardiovascular and renal physiology.

Purpose of the Study:

  • To investigate the impact of therapeutic hypothermia on renal function in awake patients with normal renal function.
  • To assess renal response to controlled hypothermia in a clinical trial setting.

Main Methods:

  • Eleven patients with normal renal function underwent endovascular cooling to 33°C for 24 hours.
  • Hourly monitoring of temperature, blood pressure, and fluid status was performed.
  • Blood samples for BUN, creatinine, and hematocrit were collected at baseline, post-treatment, and day 7.

Main Results:

  • Core body temperature decreased from 36.1°C to 33.1°C.
  • Urine output decreased by 5.1 ml/h for every 1°C drop in body temperature (p=0.001).
  • No significant changes were observed in BUN, creatinine, or hematocrit.

Conclusions:

  • Therapeutic hypothermia in patients with normal renal physiology causes a linear decrease in urine output with declining temperature.
  • Findings highlight the importance of vigilant fluid management during therapeutic hypothermia protocols.