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Updated: Jun 9, 2026

Isolation of Adipose Tissue Immune Cells
Published on: May 22, 2013
Adaptive immunity and adipose tissue biology
Denise A Kaminski1, Troy D Randall
1Division of Allergy, Immunology, and Rheumatology, Department of Medicine, University of Rochester, 601 Elmwood Avenue, Rochester, NY 14642, USA.
Abstract:
Studies of immunity typically focus on understanding how hematopoietic cells interact within conventional secondary lymphoid tissues. However, immune reactions and their regulation occur in various environments within the body. Adipose tissue is one tissue that can influence and be influenced by adjacent and embedded lymphocytes. Despite the abundance and wide distribution of such tissue, and despite a growing obesity epidemic, studies of these interactions have been only marginally appreciated in the past. Here, we review advances in understanding of lymphoid structures within adipose tissue, the relationship between adipose tissue and adaptive immune function, and evidence for how this relationship contributes to obesity-associated diseases.
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