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Related Experiment Video

Updated: Jun 9, 2026

Functional Imaging of Auditory Cortex in Adult Cats using High-field fMRI

Functional Imaging of Auditory Cortex in Adult Cats using High-field fMRI

Published on: February 19, 2014

Progesterone intoxication inducing marked sedation in a cat.

Marc P Dhumeaux¹, Elisabeth C R Snead, Germaine C Hung

¹Western College of Veterinary Medicine, University of Saskatchewan, Department of Small Animal Clinical Sciences, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4, Canada. marc.dhumeaux@usask.ca

Journal of Feline Medicine and Surgery

|September 7, 2010

Summary

A cat experienced sudden neurological issues, including lethargy and loss of balance, after ingesting progesterone capsules. Prompt supportive care led to a full recovery, marking the first reported case of progesterone toxicity causing such signs in felines.

Related Experiment Videos

Last Updated: Jun 9, 2026

Functional Imaging of Auditory Cortex in Adult Cats using High-field fMRI

Functional Imaging of Auditory Cortex in Adult Cats using High-field fMRI

Published on: February 19, 2014

Area of Science:

Veterinary Medicine
Toxicology
Endocrinology

Background:

Progesterone, a steroid hormone, plays crucial roles in reproductive cycles.
Accidental ingestion of hormonal supplements can pose risks to pets.
Neurological signs are not commonly associated with progesterone toxicity in cats.

Observation:

A 3-year-old male castrated domestic shorthair cat presented with acute severe lethargy and ataxia.
The cat's symptoms began hours after potential ingestion of progesterone-containing capsules.
Elevated serum progesterone levels were confirmed upon presentation.

Findings:

The cat exhibited neurological dysfunction consistent with progesterone intoxication.
Supportive care and a natural resolution of symptoms were observed.
Complete clinical recovery occurred without long-term sequelae.

Implications:

This case highlights progesterone toxicity as a potential cause of neurological signs in cats.
It underscores the importance of considering hormonal ingestions in toxicological assessments.
Further research may be warranted to understand the mechanisms of progesterone neurotoxicity in felines.