Ningbo thyroid dysfunction prevalence study: a cross-sectional survey in an employees-cohort

Area of Science:

• Endocrinology
• Public Health
• Epidemiology

Background:

• The prevalence and spectrum of thyroid dysfunction in China remain poorly understood.
• A population-based study was conducted to assess major thyroid dysfunctions in a stable cohort.

Purpose of the Study:

• To determine the prevalence of overt and subclinical hyperthyroidism and hypothyroidism in a Chinese adult population.
• To investigate the prevalence of thyroid dysfunction in relation to age and sex.

Main Methods:

• A cross-sectional survey involving 10,405 individuals aged 20 years and older from a stable cohort.
• Data collection included questionnaires and blood samples to assess thyroid function and history of thyroid disease.

Main Results:

• The overall prevalence of thyroid dysfunction was 4.5%. Subclinical hypothyroidism was more common in females (5.8%) than males (2.4%) and increased with age.
• Overt hyperthyroidism and hypothyroidism were uncommon (0.2% and 0.3%). Subclinical hypothyroidism prevalence was 3.4% and subclinical hyperthyroidism was 0.4%.
• Among individuals with thyroid surgery or medication, 24% had abnormal TSH levels, indicating suboptimal management in a significant portion.

Conclusions:

• Thyroid dysfunction is common in Chinese adults, with a notable prevalence of subclinical hypothyroidism, particularly in women.
• A considerable percentage of patients undergoing thyroid treatment or surgery do not maintain normal TSH levels, suggesting a need for improved monitoring and management strategies.