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Related Concept Videos

Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
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Nose and Nasal Cavity

The nose is composed of an observable exterior segment (external nose) and an internal segment within the skull known as the nasal cavity (internal nose). The external nose, visible on the face, consists of a framework of bone and hyaline cartilage enveloped in skin and muscle and lined with a mucous membrane. This structure is supported by the frontal bone, nasal bones, and maxillary bone and is supplemented by a cartilaginous framework comprising the septal nasal cartilage, lateral nasal...

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Related Experiment Video

Updated: Jun 9, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

Sinonasal mucormycosis: case report.

O Mimouni1, C-L Curto, J-B Danvin

  • 1ENT and Head and Neck Surgery Department, La Timone Adults Hospital, Marseille, France.

European Annals of Otorhinolaryngology, Head and Neck Diseases
|September 9, 2010
PubMed
Summary
This summary is machine-generated.

Diabetic ketoacidosis complicated by mucormycosis requires urgent multidisciplinary care. Prompt surgical debridement and antifungal therapy, including amphotericin B and posaconazole, are crucial for successful outcomes in sinonasal mucormycosis.

Related Experiment Videos

Last Updated: Jun 9, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

Area of Science:

  • Medical Mycology
  • Infectious Diseases
  • Ophthalmology

Background:

  • Mucormycosis is a severe fungal infection, often rapidly fatal, particularly in immunocompromised individuals like diabetic patients.
  • Diabetic ketoacidosis presents a significant risk factor for invasive fungal infections.
  • Sinonasal mucormycosis is a critical form requiring immediate intervention.

Observation:

  • A 38-year-old male with diabetic ketoacidotic coma presented with inner canthus tumefaction and mucopurulent rhinorrhea.
  • Nasal endoscopy revealed medial meatus sphaceluses, and CT scan showed a bilateral ethmoid osteolytic infectious process.
  • The patient underwent emergency endoscopic bilateral ethmoidectomy.

Findings:

  • Diagnosis of mucormycosis was confirmed.
  • Treatment involved intravenous liposomal amphotericin B followed by posaconazole for 8 months.
  • The patient showed disease resolution after comprehensive treatment.

Implications:

  • Early diagnosis and multidisciplinary management, including surgical debridement and antifungal therapy, are vital for survival.
  • Facial and cerebral CT scans are essential for diagnosing sinonasal mucormycosis.
  • Posaconazole demonstrated efficacy in this case, offering a valuable treatment option.