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[Early changes in the visual system connected with brain's aneurysm rupture].

Iwona Obuchowska¹, Jan Kochanowicz, Zofia Mariak

¹Z Kliniki Okulistyki Uniwersytetu Medycznego w Białymstoku. iwonaobu@wp.pl

|September 10, 2010

Summary

Brain aneurysm rupture often causes early visual system changes. Over half of patients with subarachnoid hemorrhage experience fundal hemorrhages, indicating the visual system

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Area of Science:

Neuroscience
Ophthalmology
Vascular Neurology

Background:

Intracranial aneurysms are a significant cause of subarachnoid hemorrhage (SAH).
Early detection of SAH complications, particularly those affecting the visual system, is crucial for patient outcomes.

Purpose of the Study:

To determine the frequency and types of early visual system alterations following brain aneurysm rupture.
To investigate the role of ocular signs as presenting manifestations of intracranial aneurysms.

Main Methods:

Study included 45 patients (34 female, 11 male) diagnosed with SAH due to aneurysm rupture.
Aneurysm identification via cerebral angiography, CT, or MR angiography.
Ophthalmologic examinations and Doppler sonography of retrobulbar vessels were conducted pre- and post-neurosurgery.

Main Results:

The majority of patients (73.3%) with aneurysms were asymptomatic at diagnosis.
Ocular signs (e.g., dilated pupil, diplopia) were present in 15% of patients before rupture.
Papilledema and intraocular hemorrhages occurred in 55.6% of SAH patients; Terson syndrome in 6.7%.

Conclusions:

Female gender may be associated with an increased risk of intracranial aneurysm formation.
Ocular signs are important presenting manifestations of brain aneurysms.
A significant proportion (over 50%) of patients with SAH post-aneurysm rupture exhibit fundal hemorrhagic changes.